Imaging techniques in biology, particularly high-performance microscopes based on light and electron beams, allow detailed insights into the processes of life. These procedures generate far more than images: Microscopy generates highly complex data sets that allow precise measurements and analyses. Today, it is not unusual for microscopes to produce several terabytes of data in a few hours. Storing, processing, and making these data publicly accessible is a significant challenge.
NFDI4BIOIMAGE, a project of the National Research Data Infrastructure, is addressing these challenges. Members of the consortium are playing a key role in the international development of a next-generation file format (NGFF). This format, “OME-Zarr,” allows large image datasets to be stored in the cloud and accessed via a web browser. At the same time, complex image data and metadata are fully preserved. The data can be streamed and loaded step by step without having to be fully downloaded.
The development is carried out in international coordination through a Request for Comments process, which ensures that the needs of the scientific community are considered. This ensures an open, international standard for biological image data that provides a sustainable foundation for the long-term use of large research data sets.
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